A Chemical Kinetic Model of Transcriptional Elongation

Fermentative Lactic Acid Production by Lactobacilli: Moser and Gompertz Kinetic Models

Lactic acid production in a batch submerged fermentation process by five Lactobacilli: bulgaricus, casei, lactis, delbrueckii and fermentum in lactose fortified whey culture were investigated. Kinetic behavior of Lactobacilli growth rate and lactose utilization was studied based on the Moser and Gompertz kinetic models. Trendline tool in Excel software was applied for fitness assessment of the ...

A look-ahead model for the elongation dynamics of transcription.

This article introduces a chemical kinetic model of the transcriptional elongation dynamics of RNA polymerase. The model's novel concept is a look-ahead feature, in which nucleotides bind reversibly to the DNA before being incorporated covalently into the nascent RNA chain. Analytical and computational methods for studying the behavior of the look-ahead model are introduced, and several approac...

Fibril Elongation by Aβ17–42: Kinetic Network Analysis of Hybrid-Resolution Molecular Dynamics Simulations

A critical step of β-amyloid fibril formation is fibril elongation in which amyloid-β monomers undergo structural transitions to fibrillar structures upon their binding to fibril tips. The atomic detail of the structural transitions remains poorly understood. Computational characterization of the structural transitions is limited so far to short Aβ segments (5-10 aa) owing to the long time scal...

Development of a Molecular Kinetic Model and Tuning of its Required Kinetic Parameters for Thermal Cracking of Light Hydrocarbons

Application of Genetic Algorithm in Kinetic Modeling and Reaction Mechanism Studies

This study is focused on the development of a systematic computational approach which implements Genetic Algorithm (GA) to find the optimal rigorous kinetic models.A general Kinetic model for hydrogenolysis of dibenzothiophene (DBT) based on Langmuir-Hinshelwood type has been obtained from open literature. This model consists of eight continuous parameters(e.g., Arrhenus  and Van't...